Table II.
The CAT activities of the delARR2PBCAT and ARR2TKCAT in transgenic mice
| DNA Construct | Founder | Sex | AP | DP | LP | VP |
|---|---|---|---|---|---|---|
| delARR2PBCAT | A0337 | M | 0 | 0 | 0 | 0 |
| A0338 | M | 0 | 0 | 0 | 0 | |
| A0339 | M | 0 | 0 | 0 | 0 | |
| A0340 | M | 530 | 1824 | 3249 | 2835 | |
| A0344 | M | 842 | 2214 | 22440 | 28062 | |
| A0349 | M | 0 | 0 | 0 | 0 | |
| A0368 | F | 0 | 0 | 0 | 0 | |
|
| ||||||
| ARR2TKCAT | A0421 | M | 493 | 1317 | 8307 | 4925 |
| A0770 | F | 0 | 0 | 0 | 0 | |
The data are represented as CAT activity (dpm/min/mg protein), which was determined in individual male founders. In the female founders, CAT activity was determined in transgenic F1 male offspring. No CAT activity was detected in any other tissue tested. AP=anterior prostate, DP=dorsal Prostate, LP=lateral prostate, VP=ventral prostate.