Table 1.
Baseline Characteristics*
All Subjects | Non-Diabetic | Diabetic | |
---|---|---|---|
(n=18) | (n=8) | (n=10) | |
Age (years) | 23±4 | 23±3 | 23±5 |
Smoker n (%) | 3 (17) | 1 (13) | 2 (20) |
BMI (kg/m2) | 25±4 | 25±6 | 25±3 |
MAP (mmHg)† | 83±6 | 84±5 | 83±6 |
Duration of Diabetes (years) | - | - | 9.8±4.1 |
Hemoglobin A1c (%) | - | - | 7.6±1.7 |
Ethinyl estradiol (µg/tablet) | 32±5 | 33±3 | 31±6 |
Progestin (mg/tablet) | 0.43±0.42 | 0.54±0.49 | 0.34±0.35 |
Progestational Activity (RBA) | 0.71±0.52 | 0.79±0.59 | 0.64±0.48 |
Androgenic Activity (RBA) | 0.75±0.56 | 0.75±0.67 | 0.74±0.48 |
PRA (ng Ang I/mL/h) | 0.5±0.45 | 0.5±0.36 | 0.6±0.53 |
Fasting Serum Glucose (mg/dL) (mmol/L) | 122±67 (6.8±3.7) | 80±5 (4.4±0.3) | 151±78 (8.4±4.3) |
Urine Sodium (mmol/24h) | 276±89 | 282±83 | 272±98 |
RPF (ml/min/1.73m2)† | 614±73 | 646±81 | 588±57 |
RVR (mmHg/mL/min/1.73m2) | 85±11 | 81±11 | 88±10 |
Abbreviations: BMI, body mass index; MAP, mean arterial pressure; PRA, plasma rennin activity; Ang I, angiotensin I; RPF, renal plasma flow
Data are expressed as mean ± standard deviation unless otherwise indicated
Median of readings at t = −10 min, −5 min and 0