Table 3.

Response to angiotensin-converting enzyme inhibition^*

	All Subjects	Non-Diabetic	Diabetic
	(n=18)	(n=8)	(n=10)
MAP Nadir (mmHg)†	78±7§	81±6§	76±7§
ΔMAP (mmHg)	−5±7	−3±5	−7±8
Peak PRA (ng Ang I/mL/h)	1.9±2.4§	2.6±3.4§	1.5±1.3§
ΔPRA (ng Ang I/mL/h)	1.4±2.2	2.1±3.1	0.9±1.0
Peak RPF (ml/min/1.73m2)‡	699±123§	733±152§	672±94§
ΔRPF (ml/min/1.73m2)	85±85	87±122	84±44
Nadir RVR (mmHg/mL/min/1.73m2)	70±11§	70±16§	69±11§
ΔRVR (mmHg/mL/min/1.73m2)	−15±9	−11±9	−18±7

Abbreviations: MAP, mean arterial pressure; PRA, plasma renin activity; Ang I, angiotensin I; RPF, renal plasma flow.

^*Data are expressed as mean ± standard deviation unless otherwise indicated

^†Mean of 2 readings at nadir of response to captopril

^‡Mean of 2 readings at peak response to captopril

^§p<0.05 compared to baseline