Table 1.

Results from the regression of log(ω) on RSA and partition (TM and EM) for each residue in 11 GPCR structures from the PDB. Significant values for partition and RSA are shown in bold. Empty values in the RSA × Partition area of the table indicate that no significant interaction effect was detected.

Gene Name	PDB ID	r2	Partition	p-value	RSA	p-value	RSA × Partition	p-value
ADBR2	2rh1	0.16	−0.28	0.0295	1.47	1.62 × 10−6
CHRM2	3uon	0.82	−1.58	< 2 × 10−16	0.12	0.34
CHRM3	4daj	0.093	−0.19	3.61 × 10−5	0.68	1.02 × 10−9
CXCR4	3oe6	0.26	−0.77	4.78 × 10−8	0.76	0.0069
DRD3	3pbl	0.14	−0.58	5.11 × 10−8	0.70	0.0024
H1R1	3rze	0.33	−0.81	1.99 × 10−7	1.77	8.51 × 10−8
OPN1SW	1kpn	0.055	0.46	4.98 × 10−4	0.49	0.11
OPRD1	4eje	0.009	0.22	0.048	0.16	0.53
OPRL1	4ea3	0.046	−0.044	0.647	0.91	5.91 × 10−5
RHO	1f88	0.017	−0.084	0.51	0.30	0.75	1.33	0.00467
S1PR1	3v2w	0.818	2.93	< 2 × 10−16	1.02	1.66 × 10−5	−1.45	9.59 × 10−5