Figure 1.

Odds ratios (ORs) and 95% confidence intervals (CIs) for risk of adenoma and subtypes of adenoma associated with replacement of 1 serving per day of various protein sources for 1 serving of total red meat during high school in the Nurses' Health Study II, United States, 1998–2007. Multivariable model adjusted for age (in years), family history of colorectal cancer (first-degree relative, yes/no), time period of endoscopy (2-year study period interval), number of reported endoscopies during the study period (1 endoscopy vs. ≥2 endoscopies), reason for most recent endoscopy (screening vs. symptoms), height, body mass index (weight (kg)/height (m)²) at age 18 years (<18.5, 18.5 to <23, 23 to <25, or ≥25), pack-years of smoking (0, 0 to 10, >10 to 20, >20 to 40, or >40), current physical activity (quintiles), physical activity during 9th–12th grades (quintiles), aspirin use (never, past, or current 1 day/week, 2–3 days/week, 4–5 days/week, or ≥6 days/week), high school energy intake (quintiles), and current cumulative average alcohol intake (quintiles).