Figure 1.

Growth of follicles from rhesus macaque (Macaca mulatta), which survived encapsulated three-dimensional culture: (A) growth patterns of primary follicles cultured in FIBRIN (alginate plus fibrin), (B) diameter of growing primary follicles at Week 13 of culture, (C) growth patterns of secondary follicles cultured in alginate and (D) diameter of slow- and fast-growing follicles at Week 5 for secondary follicle culture. Significant differences over time (lowercase) or between-follicle categories (uppercase) are indicated by different letters (P < 0.05). Data are presented as the mean ± SEM with 7 animals per group. *P < 0.05.