Table 1.

Fotemustine before temozolomide era.

Authors	Number of Patients	Schedule	Toxicity Grade 3–4 Thrombocytopenia and Leucopenia	Response Rate
Frenay et al. [15]	38	Standard	23 and 17% of patients	23%
Khayat et al. [16]	8	Intra-arterial	14% of patients	12.5%
Malhaire et al. [17]	22	Standard	2 and 4 patients	50%
Mousseau et al. [18]	34	Standard	NA	70%
Boiardi et al. [19]	16	Escalating doses and procarbazine	1 and 1 patients	50%
Fazen-Döner et al. [20]	31	Standard and dacarbazine	1 and 3 patients	54.8%