Table 2.
Fotemustine post-temozolomide era.
| Authors | Number of Patients | Schedule | Toxicity | Response Rate |
|---|---|---|---|---|
| Brandes et al. [22] | 43 | Standard | 20.9 and 16% of patients | 42% |
| Fabrini et al. [23] | 50 | Standard | 4 and 1 patients | 62% |
| Silvani et al. [24] | 54 | Combination of fotemustine and procarbazine | 4 and 2 patients | |
| Fabi et al. [26] | 40 | 65 to 100 mg/m2 of fotemustine | 8 and 6 patients | 47.5% |
| Fabi et al. [26] | 40 | 60 mg/m2 of fotemustine, every 3 weeks | 3 and 4 patients | 52.5% |
| Addeo et al. [9] | 40 | 80 mg/m2 of fotemustine, every 2 weeks | 7 and 3.5% of patients | 65% |