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. 2012 Mar 14;4(1):307–322. doi: 10.3390/cancers4010307

Table 2.

Comparison of preoperative with postoperative radiation in prospective trials (from Gomez et al. [43] and comparing this postoperative radiation trial with studies from the Southwest Oncology Group [31,32] and JCOG 9806 [36]).

Outcome Variables Preoperative Concurrent Chemoradiation Postoperative Concurrent Chemoradiation Current Study
SWOG 94-16 JCOG 9806
Adherence to treatment regimen 75% * 76% 78%
Operative mortality rates 2.4% 3.5% 0
R0/R1 resection rates 92% ** 95% 100%
Locoregional control rates 85% *** 87% 76%
5-year overall survival rates 44% 56% 50%

* Defined as percentage of patients undergoing induction chemoradiation followed by thoracotomy as a proportion of the total number of eligible patients; ** Defined as percentage of patients in whom R0/R1 resection was achieved as a proportion of those patients who proceeded to surgery *** Reported as local control. Reported as initial site of failure; SWOG, Southwest Oncology Group; JCOG, Japan Clinical Oncology Group.