Table 2.
Outcome Variables | Preoperative Concurrent Chemoradiation | Postoperative Concurrent Chemoradiation Current Study | |
---|---|---|---|
SWOG 94-16 | JCOG 9806 | ||
Adherence to treatment regimen | 75% * | 76% | 78% |
Operative mortality rates | 2.4% | 3.5% | 0 |
R0/R1 resection rates | 92% ** | 95% | 100% |
Locoregional control rates | 85% *** | 87% † | 76% |
5-year overall survival rates | 44% | 56% | 50% |
* Defined as percentage of patients undergoing induction chemoradiation followed by thoracotomy as a proportion of the total number of eligible patients; ** Defined as percentage of patients in whom R0/R1 resection was achieved as a proportion of those patients who proceeded to surgery *** Reported as local control. † Reported as initial site of failure; SWOG, Southwest Oncology Group; JCOG, Japan Clinical Oncology Group.