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. 2012 Mar 1;4(1):244–256. doi: 10.3390/cancers4010244

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© 2012 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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(A) Imaging of a 22 year-old female (case 9) with glioblastoma, previously treated with tumor resection followed by conventional radiotherapy and temozolomide. T1-weighted contrast enhanced MR image showing irregular enhancement in the right occipital lobe. MET-PET and FLT-PET show intense uptake of tracer in the lesion. Recurrent glioblastoma was pathologically confirmed by surgery; (B) Imaging of 61 year-old female (case 21) with glioblastoma, previously treated with tumor resection followed by conventional radiotherapy and temozolomide. T1-weighted contrast enhanced MR image showing enhanced mass in the left temporal lobe. MET-PET shows mild uptake of tracer and FLT-PET shows faint uptake of tracer in the lesion. Necrosis and gliosis dominant tissue was pathologically confirmed by surgery.