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. 2012 Apr 26;4(2):490–503. doi: 10.3390/cancers4020490

Figure 3.

Figure 3

Reactivity of spleen T cells from ret transgenic mice upon antigen-unspecific stimulation. Splenocytes from tumor free (ret ) or tumor bearing transgenic mice (ret tu) or non-transgenic littermates (wt) were incubated overnight with anti-CD3 and anti-CD28 mAbs. The amount of secreted IL-2 (a) and IFN-γ (b) was determined by ELISA. Data (mean ± SEM of 4–5 mice per group) are expressed as pg/mL. * p < 0.05, ret versus wt or ret versus ret tu groups. ** p < 0.05, ret versus ret tu groups.