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. 2012 Jun 18;4(2):581–600. doi: 10.3390/cancers4020581

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© 2012 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Frequencies of regulatory cell subsets present within the peripheral blood of ovarian cancer patients. (A) The gating strategy employed to identify regulatory T cells (CD4+CD25^hiFOXP3+CD127−) present in the PBMCs; (B) Comparison of regulatory T cell subset frequencies between healthy controls (n = 5) and ovarian cancer patients undergoing chemotherapy (n = 5); (C) Frequency fluctuations of regulatory T cell subsets of patients over the course of chemotherapy. The dotted line represents the mean frequency of the healthy controls. Comparison of regulatory T cell subset frequencies between controls and patients: * p < 0.05.