Table 5.
Distributions of susceptible and protective HLA-DRB1 and -DQB1 genotypes and haplotypes according to the gender of T1D in four age at onset groups
| Age categories at onset | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype/haplotype | Gender | 1-5 | P | OR(CL) | 6-10 | P | OR(CL) | 11-15 | P | OR(CL) | 16-20 | P | OR(CL) | Control |
| Genotype DQB1*0301/0501 | M(n:0) | 0 | NS | - | 0 | NS | - | 0 | 0.4 | - | 0 | 0.07 | - | 12 |
| F(n:4) | 0 | 0 | 4 | 3 | 7 | |||||||||
| Haplotype DRB1*0401-DQB1*0302 | M(n:30) | 13 | 0.07 | - | 8 | 0.1 | - | 10 | 0.9 | - | 0 | NS | - | 0 |
| F(n:1) | 0 | 0 | 0 | 0 | 1 | |||||||||
| DRB1*0301-DQB1*0201 | M(n:18) | 4 | 0.1 | - | 4 | 0.007 | 0.121(0.02-0.55) | 10 | 0.3 | - | 0 | NS | - | 11 |
| F(n:34) | 8 | 15 | 4 | 0 | 5 | |||||||||
| DRB1*1501-DQB1*0601 | M(n:0) | 0 | NS | - | 0 | NS | - | 0 | NS | - | 0 | 0.01 | - | 15 |
| F(n:4) | 0 | 0 | 0 | 4 | 6 | |||||||||
M; Male, F; Female, NS; Not significant and P; Value of Fisher’s exact test.