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. Author manuscript; available in PMC: 2013 Jul 16.

Published in final edited form as: Chem Biol Drug Des. 2012 Jan 30;79(4):470–477. doi: 10.1111/j.1747-0285.2011.01288.x

Table 2.

Variations of aldehydes and praziquantel derivatives 9(a-g) graphic file with name nihms-343095-t0017.jpg

Entry	R²CHO 3(a-g)	Product^a	9 (a-g)	Yield (%)^b
1			9a	21
2			9b	29
3			9c	33
4			9d	34
5			9e	23
6			9f	16
7			9g	17

^a

Relative stereochemistry as drawn.

^b

Overall isolated yield for two steps.