Table 3.
Tick molecules interfering with Babesia acquisition and/or transmission.
Name | Supposed function | RNAi effect on the pathogen | References |
---|---|---|---|
Longicin | Defensin | Increased acquisition and transovarial transmission | Tsuji et al., 2007 |
Longipain | Cysteine protease | Increased acquisition and transovarial transmission | Tsuji et al., 2008 |
H. longicornis vitellogenin receptor (HIVgR) | Uptake of vitellogenin | Decreased transovarial transmission | Boldbaatar et al., 2008 |
Subolesin (SUB) | Component of the immune signaling pathways | Decreased acquisition | Merino et al., 2011 |
Tick receptor for OspA (TROSPA) | Unknown | Decreased acquisition | Antunes et al., 2012 |
Calreticulin | Protein folding and signaling | Decreased acquisition | Antunes et al., 2012 |
Serum amyloid A | Response to inflammation | Decreased acquisition | Antunes et al., 2012 |