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. 2013 Jul 16;8(7):e68695. doi: 10.1371/journal.pone.0068695

Table 2. Summary relative estimates for glioma in women.

Exposure Categories Heterogeneity
Risk factors Highest(min to mix) vs. Lowest(minto mix) Number of studies(Reference) Pooled RR(95% CI) PQ I2 PEgger’s
OC Ever vs. Never 6 (20–24, 41) 0.707(0.604–0.828) 0.806 0.0% 0.144
HRT Ever vs. Never 6 (20–24, 29) 0.683(0.577–0.808) 0.744 0.0% 0.252
Menopausal status Postmenopausal vs. Premenopausal 5 (23, 24, 27, 29, 42) 0.959(0.670–1.375) 0.031 62.4% 0.699
Parous status Parous vs. nulliparous 6 (21, 22, 24, 25–27) 0.837(0.674–1.040) 0.005 69.9% 0.779
Age at menarche Oldest (≥14) vs. Youngest(≤11 to ≤12) 6 (21–24, 27, 41) 1.401(1.052–1.865) 0.038 57.6% 0.076
Age at menopause Oldest(≥50 to ≥53) vs. Youngest(≤40 to ≤50) 5 (21–24, 27) 0.972(0.782–1.209) 0.714 0.0% 0.093
Age at first birth Oldest(≥30 to ≥35) vs. Youngest(≤20 to ≤25) 6 (21, 22, 24–27) 1.153(0.879–1.513) 0.105 45.1% 0.146