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. 2013 Jul 16;8(7):e68804. doi: 10.1371/journal.pone.0068804

Figure 5. The defect in B cell development caused by PP4 deficiency can be rescued by Ig transgene expression.

Figure 5

(A) Flow cytometric profiles of: total BM lymphocytes from WT, cKO and cKO/IgHEL mice (n = 3–5/group) analyzed for B220 vs IgM (far left panel) or B220 vs CD43 (middle left panel); or B220+CD43+ BM lymphocytes analyzed for CD24 vs BP-1 (middle right panel); or B220+CD43− BM lymphocytes analyzed for IgM vs IgD (far right panel). (B) Quantitative cell count analysis of Frs. A to C cells from the mice in (A). (C) Quantitative cell count analysis of Frs. D to F cells from the mice in (A). For B and C, data are the mean ± SD (n = 3–5/group). Results are representative of two independent experiments (*p≤0.05, **p≤0.005; ns, not significant).