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. 2013 Jul 16;8(7):e68154. doi: 10.1371/journal.pone.0068154

Figure 7. Luxol Fast Blue histochemical assessment of cardiomyocyte myofilament lysis.

Figure 7

Luxol Fast Blue staining for the analysis of cardiomyocyte myofilament integrity was performed in left ventricular free walls from 12 month old WT (panel A), 12 month old NTT-MMP-2 transgenic mice (panel B) and 12 month old hearts expressing the full length MMP-2 cDNA (panels C and D). Myofilament lysis results in Luxol Fast Blue staining. There is little Luxol Fast Blue staining in the 12 month old WT or NTT-MMP transgenic hearts while there is abundant Luxol Fast Blue staining in the 12 month old full-length MMP-2 transgenic hearts, consistent with myofilament lysis. (X250).