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. 2013 Jul 16;8(7):e68335. doi: 10.1371/journal.pone.0068335

Table 8. Down-regulated genes in the MCA that are common between ‘hypertension only’ and ‘hypercholesterolemia plus sham’ rabbits (both vs. sham controls) with greater than 4-fold change.

Gene Gene Symbol Corrected p-value Hypertension only Hyperchole-sterolemia plus sham Hypertension plus hyperchole-sterolemia
Fold Change Fold Change Fold Change
forkhead box N1 FOXN1 0.00048 −26.20 −56.89 −45.12
Ribosomal protein S3a-like LOC100354966 <0.00001 −16.54 −5.74 −1.83
ADAM metallopeptidase with thrombospondin type 1 motif, 17 ADAMTS17 0.00001 −15.85 −7.25 −3.06
peptidylprolyl isomerase G (cyclophilin G) PPIG <0.00001 −12.61 −6.20 −1.81
hematopoietic prostaglandin D synthase HPGDS 0.00043 −12.38 −21.44 −13.63
large subunit GTPase 1 homolog (S. cerevisiae) LSG1 <0.00001 −7.69 −20.38 −1.93
mitochondrial ribosomal protein L15 MRPL15 <0.00001 −6.97 −23.01 −9.57
translocase of outer mitochondrial membrane 5 homolog (yeast) TOMM5 0.00014 −5.67 −4.05 −1.60
ribosomal protein L26 RPL26 0.00016 −5.27 −14.60 −2.81
family with sequence similarity 177, member A1 FAM177A1 0.00016 −4.41 −10.75 −1.95
Proteasome (prosome, macropain) 26s subunit, non-ATPase, 4 PSMD4 0.00005 −4.34 −17.67 −11.67
Aggrecanase-2 ADAMTS-11 0.00005 −4.26 −9.31 −6.51
BRCA2 and CDKN1A interacting protein BCCIP <0.00001 −4.06 −14.00 −2.58