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. 2013 Jul 16;8(7):e65590. doi: 10.1371/journal.pone.0065590

Table 2. Cross-recognition results for six different Melan-A-specic CTL clones in a chromium release assay: the logarithm of the relative functional avidity of the ELX analogs to ELA is given.

Seqa Melan-A-specic CTL clones
203-R7 25-R3 203-R2b 203-R1 203-R3 25-R35
ELA 0.00c 0.00d 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ELS −0.59 0.14 −0.41 0.13 −0.07 0.00 −0.01 0.10 −0.99 0.01 −2.44 0.50
ELT −0.19 0.32 −2.17 0.11 0.09 0.00 −0.05 0.15 −1.88 0.08 −1.59 0.62
a

The P1-P3 peptide sequence of the ELX analog.

b

Only one experiment was done with the 203-R2 clone.

c

The logarithm of the relative functional avidity of the ELX analogs compared to ELA was calculated as log10(EC50ELA/EC50ELX). A value of −1.00 means that the molar concentration of the ELX peptide needs to be 10 times higher than ELA to achieve the same activity, i.e. 50% of maximal lysis. The average over the independent experiments for each CTL clone is given.

d

Standard deviation. By the denition of the score, the standard deviation for ELA is zero.