Figure 2. Tumor development in p53^+/R172H mice. Abundance of lymphomas, sarcomas and carcinomas were dictated by PML abundance in p53^+/R172H mice, as indicated by the proportion of tumors (calculated as the number of tumors of a specific tumor type/total number of tumors and expressed as a percentage) in a Venn Diagram presentation (A). Tumor prevalence as determined on an individual mouse basis indicated the extensive perturbation of the hematological niche in mice with PML; however, in mice without PML, sarcomas dominated (B).