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Figure 2. Model of the wild-type and mutant ternary complexes of Cdc34-Ub-Sic148–52. (A) A consensus model for the wild-type complex Cdc34-Ub-Sic148–52, as well as the distribution of the charged residues in the proximity of the Sic1 peptide. (B) The effects induced by the mutation T48R (middle panel), T49D (right panel) compared with the wild-type Sic148–52 (left panel). Ub-Rs denote ubiquitin arginines.
