Table 4. Parameters of the lifespan and tumorigenesis in female 129/Sv mice exposed to various light regimens.
| Light regimen | |||
|---|---|---|---|
| Parameters | LD | LL | Ratio |
| Number of mice | 46 | 46 | |
| Mean lifespan (LS), days | 763 ± 21.8 | 701 ± 20.7a | −8.1% |
| Median | 795 | 722 | −9.2% |
| Mean LS of last 10% survivors | 967 ± 10.2 | 867 ± 11.0b | −10.3% |
| Maximum lifespan, days | 997 | 902 | −9.5% |
| Aging rate (α), days−3 | 7.97 (6.74; 8.23) | 9.39 a (8.83; 10.9) | +1.2 times |
| MRDT, days | 87 (84; 103) | 74a (63; 79) | −1.2 times |
| The age of the 1st tumor detection, days | 500 | 442 | |
| Effective number of mice | 45 | 43 | |
| Number of tumor-bearing mice | 37 (86.7%) | 35 (81.4%) | |
| Number of fatal tumor-bearing mice | 31 (68.9%) | 23 (53.5%) | |
| Mean LS of tumor-bearing mice, days | 800 ± 20.6 | 745 ± 17. 4a | −6.9% |
| Localization and type of tumors | |||
| Uterus: | |||
| hemangioma | 6 | 12 | p = 0.065 |
| sarcoma | 30 | 20 | p = 0.079 |
| Malignant lymphoma | 1 | 2 | |
| Lung: | |||
| adenoma | - | 2 | |
| adenocarcinoma | 1 | 1 | |
| Stomach: adenocarcinoma | 1 | - | |
| Bladder: papilloma | - | 1 | |
The difference with the control of the LL: ap < 0.05; bp < 0.001.