Skip to main content
. Author manuscript; available in PMC: 2014 Jul 10.
Published in final edited form as: Neuron. 2013 Jun 6;79(1):69–81. doi: 10.1016/j.neuron.2013.05.018

Figure 2.

Figure 2

Two components of the voltage-induced hair bundle motion. (A) Depolarization from −84 to +56 mV evoked biphasic bundle motion. The MT channel blocker FM1-43 (7.5 μM) blocked a positive component of the motion thereby increasing the negative component. The difference motion (control – FM1-43), reflecting the MT channel component is entirely positive (towards abneural edge). (B) The same depolarization in another SHC elicited a biphasic bundle motion that became positive and sustained with application of 10 mM Na+ salicylate. The difference motion (control - salicylate) is entirely negative (away from bundle’s tallest edge). (C) MT currents in these same two SHCs. Top is SHC in (A) without (black trace) and with (red trace) FM1-43 which blocks 90 per cent of the current. Bottom is SHC in (B) without (black trace) and with (red trace) salicylate.