Phenotype of adult Kiss1Cre/Cre males. A, Testicular weight (n = 10-12). B, LH in GDX mice (n = 4-5). C, T (n = 9-22). D, FSH in intact mice (n = 7-19). **, P < .005; ***P < .0001; A and D were analyzed with 1-way ANOVA with Tukey's multiple-comparison test. B and C were analyzed with Kruskal-Wallis nonparametric test because some samples were out of the range of the assay. Abbreviation: n.s., not statistically significant.