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Dicentric chromosome induction leads to global genomic rearrangement. a Spectral karyotype (SKY) analysis of 3T3-lacO cells expressing GFP-LacI or GFP-CENP-T-ΔC-LacI at a time point 3 days after removal of IPTG. Representative images of chromosomes involved in translocations are pseudo-colored. b Quantification of the rates of chromosome translocations in a
