Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Jul 1;2013:964743. doi: 10.1155/2013/964743

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Mridul Roy et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Possible pathways for growth factor mediated tumorigenesis. Activation of receptor can lead to cell proliferation, survival, angiogenesis, and metastasis via four possible pathways; the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway, Ras/Raf/mitogen-activated protein kinase (MAPK) pathway, nitric oxide synthase (NOS), and prostaglandin (PG) involving phospholipase Cγ (PLCγ)/protein kinase C (PKC) pathway and signal transducer and activator of transcription (STAT) pathway.