Table 2.
Additional human RMS cell lines reported and used by a single research group.
| Cell lines | Origin | Previous treatment | Karyotype | Additional information | Reference |
|---|---|---|---|---|---|
| EMBRYONAL HISTOLOGY | |||||
| DI-OH1 | Primary tumor, pediatric male | Unknown | 50, XY, +2, +8, +11 | Undetectable telomerase activity | Kleideiter et al. (8) |
| VK | Primary tumor of 20-year-old female with localized disease | None | 46, XX, t(1;11)(p36.31;p11.2), t(10;11)(q22.3;p11.2), t(1;10)(p36.31;q22.3), t(2;17)(q23;p13.3), t(4;19)(q35.1;q13.1), t(14;17)(q32.3;q21.31) | Urumov and Manolova (11) | |
| RMS-GR | Relapsed urogenital tract tumor of 75-year-old male | Yes | 59, XY, −1, +der(1)t(1;?)(q31;?), +del(1)(p13), +del(3)(p13), +del(3)(p13), der(3)t(3;19)(p11;q11), +der(8)t(8;?)(p23;?), +M | Upregulation of mdr1 | Fernandez et al. (6) |
| TS-RM-1 | Unknown | Unknown | Chromosome number 88−98 der(3)t(1;3)(q12;p12–14), 16q-, 17q+, and 21q+ | Kaneko et al. (13) | |
| YN | 15-year-old male with paratesticular tumor | Unknown | Unknown | Motoyama et al. (12) | |
| ALVEOLAR HISTOLOGY | |||||
| CB-NJR | Unknown | Unknown | Unknown | Ozkaynak et al. (10) | |
| FL-OH1 | Primary tumor, pediatric male | Unknown | 60–89, XY, many clonal and non-clonal aberrations, negative for t(1;13), t(2;13) | High telomerase activity | Kleideiter et al. (8) |
| HA-OH1 | Relapsed tumor, pediatric female | Unknown | 78–87, XXX, der(1), t(1;13), der(1), t(1;13), i(q), del(3), 4q+, del(6), −13, [cp4] | Low telomerase activity | Kleideiter et al. (8) |
| HUMEMS | 13-year-old female with breast primary, cell line established from pleural fluid | t(2;13) | Ohi et al. (14) | ||
| NRS-1 | 7-year-old female with forearm primary | Unknown | t(2;13) | Ogose et al. (15) | |
| RH7 | Primary tumor | Unknown | Morton and Potter (23) | ||
| UISO-RS-3 | 28-year-old female with buttock primary, cell line established from a malignant pleural effusion | Yes | 43–49, X, Philadelphia 22 chromosome (70% of metaphase spreads) | Madsen et al. (10) | |
| Not named | 14-year-old female with chest wall primary, cell line established from malignant effusion | Unknown | 41–49, t(2,13)(q37;q14), double minute chromosomes | Garvin et al. (7) | |
| PLEOMORPHIC HISTOLOGY | |||||
| HS-RMS-1 | 26-year-old male with gluteal tumor | Unknown | Pseudotetraploid | Sonobe et al. (16) | |
| HS-RMS-2 | 85-year-old female with gluteal tumor | Unknown | 8 amplified regions including oncogenes JUN, MYC, CCND1, INT2, MDM2, and MALT | Takaoka et al. (17) | |
| UNKNOWN HISTOLOGY | |||||
| HUS-2 | 80-year-old female with chest wall mass | No | Modal chromosome number of 58 | Cook et al. (5) | |