Table 1.
Demographics of patients recruited to study. Values expressed as means and 95% confidence intervals.
| Severe sepsis (ICU) | Infection | Control | ||
|---|---|---|---|---|
| ICU admission | Day 7 ICU | |||
| N | 54 | 32 | 53 | 20 |
| Median age (yrs) | 71 (60–76) | 72 (61–79) | 71 (49–81) | 30 (27–33) |
| Gender | ||||
| Male | 23 (54%) | 16 (53%) | 33 (62%) | 8 (40%) |
| Female | 27 (46%) | 14 (47%) | 20 (38%) | 12 (30%) |
| Patient type | ||||
| Surgery | 23 | 20 | — | — |
| Medical | 31 | 12 | — | — |
| Bacteraemia | ||||
| Gram positive | 10 | — | 24 | — |
| Gram negative | 3 | — | 29 | — |
| APACHE II | 21 (19–22) | 18.4 (15.7–21.7) | — | — |
| SOFA | 12 (9.1–15) | 8.9 (6.9–10.7) | — | — |
| SAPS II | 52 (47–57) | 50 (42–58) | — | — |
| Septic shock | 42 (84%) | 15 (50%) | — | — |
| Respiratory infection | 23 (46%) | 6 (20%) | — | — |
| Abdominal infection | 14 (28%) | 16 (53%) | — | — |
| Other infection | 13 (26%) | 8 (27%) | — | — |
SOFA: sequential organ failure assessment score; SAPS II: simplified acute physiology score; APACHE: acute physiology and chronic health evaluation.