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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Cancer. 2012 Jan 17;118(17):4321–4330. doi: 10.1002/cncr.27378

Table 2.

Methotrexate-related toxicities during the glucarpidase course

Common Toxicity Criteria Grade (% of patients)
Toxicity 3 4
Serum creatinine elevation 6 (30%) 1 (5%)
Oral mucositis 1 (5%) -
Vomiting 2 (10%) -
Diarrhea - -
Myelosuppression 1 (5%) 2 (10%)
Infection 4 (20%) -