Table 2.

Subject disease profile and time course

Group	Animal	Disease type	Survival time (weeks pi, pm)	Onset ABR abnormality (weeks pi, pm)	Onset VEP abnormality (weeks pi, pm)	Onset clinical symptoms (weeks pi, pm)	Terminal virus load plasma (copies/mL)	Terminal virus load CSF (copies/mL)	Symptoms
VM (n=6)	98C053	S	31, 57	–	–	–	9, 800	17, 900	–
	98D264	C	16, 42	12, 38	8, 34	13, 39	43,151,780	25,385,640	Severe tremor and ataxia
	98C065	C	15, 41	12, 38	15, 41	13, 38	49,258,480	25,138,180	Severe tremor and ataxia
	98D276	S	31, 57	–	–	–	6,444,920	112,920	–
	98C095	S	30, 56	21, 47	30, 56	24, 50	73,972,400	82,550	Mild weight and appetite loss
	98C088	S	31, 57	8, 34	–	–	37,747,380	98,540	–
V (n=5)	98D388	S	31, NA	8, NA	8, NA	–	11,240	7,080	–
	98C001	C	29, NA		12, NA	16, NA	54,186,180	138,928,140	Untreatable diarrhea and severe weight loss
	98C089	C	13, NA	12, NA	4, NA	13, NA	30,618,660	175,497,620	Acute seizures. paralysis
	98D321	S	30, NA	12, NA	12, NA	25, NA	17,828,120	22,200	Mild tremor
	98C025	S	31, NA	–	–	–	27,318,940	272,820	–
M (n=5)	98C067	NA	NA, 59	–	–	NA, 44	NA	NA	Mild tremor
	98C070	NA	NA, 34	–	–	NA, 24	NA	NA	Leg infection at injection site
	98C097	NA	NA, 59	–	–	NA, 59	NA	NA	Mild tremor
	98C110	NA	NA, 34	–	–	NA, 18	NA	NA	Leg infection at injection site
	98C042	NA	NA, 59	–	–	–	NA	NA	–