Table 3.
Averaged fast synaptic inputs of preoptic area (AVPV/PeN) and Arc nucleus Kiss1 neurons of OVX and OVX + E2 mice
| OVX | OVX + E2 | ERα | |
|---|---|---|---|
| AVPV/PeN | |||
| EPSC frequency (Hz) | 0.7 ± 0.2 (n = 15) | 1.1 ± 0.2 (n = 18) | 0.7 ± 0.1 (n = 13) |
| EPSC amplitude (pA) | 19.6 ± 1.1 (n = 15) | 20.2 ± 0.9 (n = 18) | 20.8 ± 1.6 (n = 13) |
| IPSC frequency (Hz) | 0.2 ± 0.1 (n = 13) | 0.3 ± 0.1 (n = 15) | 0.3 ± 0.1 (n = 10) |
| IPSC amplitude (pA) | 24.4 ± 1.5 (n = 13) | 33.9 ± 3.2 (n = 15)* | 23.1 ± 2.6 (n = 10) |
| ARC | |||
| EPSC frequency (Hz) | 2.3 ± 0.4 (n = 24) | 1.7 ± 0.4 (n = 14) | 2.6 ± 0.9 (n = 8) |
| EPSC amplitude (pA) | 26.1 ± 2.4 (n = 24) | 22.7 ± 2.0 (n = 14) | 23.8 ± 2.1 (n = 8) |
| IPSC frequency (Hz) | 0.3 ± 0.1 (n = 18) | 0.3 ± 0.1 (n = 11) | 1.4 ± 0.5 (n = 8)** |
| IPSC amplitude (pA) | 60.0 ± 7.8 (n = 18) | 26.3 ± 1.9 (n = 11)** | 40.3 ± 4.8 (n = 8) |
Mean ± SE, *p < 0.05, **p < 0.005. n represents number of cells. Total number of mice: OVX females, 6 for AVPV/PeN and 9 for Arc; OVX + E2 females, 6 for AVPV/PeN and 6 Arc; female Kiss1-Cre/GFP/ERαflox/flox, 4 for AVPV/PeN and 4 for Arc.