Figure 1.

Quantitative real-time polymerase chain reaction (PCR) of Wnt2 and secreted frizzled-related protein 4 (sFRP4) messenger RNA (mRNA) expression in placentas of the 2 groups. A, Compared to the control group, Wnt2 mRNA is downregulated in severe preeclampsia (PE) group. B, No significant difference was detected in sFRP4 mRNA expression between the 2 groups. For comparison of the 2 groups, the values of the control group were arbitrarily set at 1. Bars indicate the mean values ± standard deviation (SD) of the 30 cases performed in triplicate. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as an internal control. **Indicates P value< .01; ns, no significant difference.