Figure 1.

Ex vivo characterization of ectopic and orthotopic colon carcinoma CT26 implanted in mice. (a) Tumours were harvested from Balb/c mice at the indicated days and weighed. The means ± SEM of 5 tumours are presented. The asterisks indicate a significant difference between the orthotopic (squares) and the ectopic group (circles) using the Mann Whitney test. Photographs of a representative tumour on day 21 are shown in (b) for the ectopic implantation and in (c) for the orthotopic tumour (scale bar, 5 mm).