Figure 3.

Developmental time course of transcript levels of genes within the duplication in Plp1dup compared with wild-type mouse brain. Levels of mRNA expressed from (A) Tceal3, (B) Tceal1, (C) Morf4l2, (D) BC065397, and (E) Glra4 were measured by qRT-PCR of total RNA prepared from Plp1dup brain and expressed as RQ with the average of P7 wild-type used as the calibrator. Total RNA was prepared at postnatal days indicated (Plp1dup, n = 3; wild-type, n = 3 at each time point). Open bars represent wild-type; black bars, Plp1dup. Controls are described in Materials and Methods. *p < 0.05. **p < 0.01. ***p < 0.001.