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. 2013 Jul 17;33(29):11788–11799. doi: 10.1523/JNEUROSCI.1336-13.2013

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Copyright © 2013 the authors 0270-6474/13/3311788-12$15.00/0

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Figure 9. — Electron micrographs of spinal cords from 6 month wild-type and Plp1dup mice. Representative electron micrographs of transition between ventral funiculus and ventral gray matter of wild-type mouse (A) and Plp1dup mouse (B–F) at 6 months of age. Ax, Axon; MG, microglial cell; AG, astrogliosis; DF, large unmyelinated axon (degenerating fiber) packed with neurofilaments; PN/IN with arrow, paranode/internode. B, Arrow points to a degenerating axon being engulfed by a microglial cell. D, Arrows point to a cluster of degenerating fibers. F, The axon (Ax) is myelinated on one side of a node but unmyelinated on the other. Scale bar, 1 μm.