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. 2013 Jul 17;33(29):11916–11931. doi: 10.1523/JNEUROSCI.1760-13.2013

Figure 3.

Figure 3.

Adf-1 functions downstream to CaMKII signaling to regulate dendrite growth in RP2 motor neurons. A, Representative RP2 dendrite reconstructions for Adf-1 and CaMKII genetic interactions. B, C, Volumetric Sholl analysis and the measurement of dendrite branch number and total dendrite length for CaMKII[T287D], Adf-1[S64/184A], and their combination, compared with control neurons. D, E, Volumetric Sholl analysis and measurements of dendrite branch number and length for the CaMKII peptide inhibitor Adf-1[S64/184D] and their combination compared with control neurons. The expression of Adf-1[S64/184D] significantly increases dendrite branch number in a CaMKII-inhibited background (*p < 0.05 for pairwise comparison after Bonferroni's correction). F, G, Branch-order analysis in experiments to test genetic interaction between CaMKII and Adf-1.