Table 2.
Regions showing altered frequency power distribution in male IBS patients compared with male HCs
| ROI | Hemisphere | Cluster size (voxels) | p-value | T | Z-score | x | y | z |
|---|---|---|---|---|---|---|---|---|
| Male HCs versus male IBS (amplitude of HF vs MF) | ||||||||
| aINS | L | 23 | 0.024 | 3.48 | 3.45 | −34 | 14 | −14 |
| mINS | L | 18 | 0.022 | 3.55 | 3.52 | −40 | −4 | 0 |
| pINS | L | 92 | 0.008 | 4.02 | 3.97 | −40 | −8 | 0 |
| mINS | R | 26 | 0.017 | 3.9 | 3.85 | 40 | −8 | 0 |
| Male HCs versus male IBS (amplitude of HF vs LF) | ||||||||
| pINS | L | 22 | 0.032 | 4.02 | 3.97 | −38 | −10 | 6 |
ROI analysis was applied by thresholding whole-brain fALFF activation maps at an uncorrected significance threshold of p < 0.001 and using the small volume correction procedure in SPM8. Results were considered significant at cluster threshold of p < 0.05 corrected for voxel wise error rate. MNI coordinates (x,y,z) for peak voxels show significance.