Table. Characteristics of 3 rhesus macaques in study of BSE-associated prion-amyloid cardiomyopathy*.
Primate | Age at inoculation | Time to clinical disease, mo | Disease duration, wk | Cardiac PrPSc | Signs of cardiac distress at autopsy |
---|---|---|---|---|---|
BSE inoculated | 8 y | 49 | 4 | Neg | Neg |
5 y | 59 | 18 | Pos | Pos | |
1 y | 61 | 4 | Neg | Neg | |
Control | 8 mo | NA | NA | Neg | Neg |
17 y | NA | NA | Neg | Neg | |
19 y | NA | NA | Neg | Neg |
*BSE, bovine spongiform encephalopathy; Neg, negative; Pos, positive; NA, not applicable.