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. 2013 Jul;19(7):1138–1141. doi: 10.3201/eid1907.130313

Table. Details for samples used in a study of the amplification of multidrug-resistant tuberculosis, resulting from competitive growth advantage, during treatment of a drug-sensitive Mycobacterium tuberculosis strain in a mixed infection*.

Sample
Isolate
Smear
Resistance
MIRU-VNTR
Bronchoalveolar lavage, obtained February 2008 S + None 3243323125153242244235-1
Sputum, obtained April 2008 S ++ None 3243323125153242244235-1
Sputum, obtained June 2008 R +++ INH, ETB -2434233251533445-443330
Co-cultures 1) broth culture + INH, 2) colonies from broth culture − INH on plate with INH, 3) colonies from broth culture + INH on plates − INH and 4) colonies from broth culture + INH on plates − INH R NA INH -2434233251533445-443330
Co-cultures 5) broth culture − INH and 6) colonies from broth culture − INH on plates − INH S NA NA 3243323125153242244235-1

*MIRU-VNTR, mycobacterial interspersed repetitive unit–variable number tandem repeat; S, drug sensitive; +, ++, and +++, relative burden of acid-fast bacilli; R, drug resistant; INH, isoniazid; ETB, ethambutol; NA, not applicable.

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