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. Author manuscript; available in PMC: 2013 Jul 17.
Published in final edited form as: Chem Biodivers. 2011 Sep;8(9):1571–1615. doi: 10.1002/cbdv.201100033

Fig. 11. Structure of the 1,N6-εdA adduct (X14) opposite dG, in the 5′-C13X14C15-3′ sequence.

Fig. 11

The top panel shows the three base pairs with the 1,N6-εdA adduct (syn conformation) located in the major groove. The bottom panel shows the 1,N6-εdA (syn)·G (anti) base pair alignment viewed down the axis and the two H-bonds that stabilize this base pair. Reproduced with permission from [92] (© 2002 American Chemical Society).