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Loss of heterozygosity in favor of the mutant allele of IDH1 correlates with a decreased copy number of the IDH1 locus. (a) IDH sequencing on the IDH1-mutant anaplastic oligoastrocytoma and derived IDHmt brain tumor stem cell line (BT142). (b) Copy number assay of the IDH1 locus on heterozygote and homozygote BT142.
