Figure 4. Reduced abortion rates in mice with T. gondii ESA injection at G5 by adoptively transfering of Tregs isolated from mice with T. gondii ESA injection at G15.

(A) Representative pictures of uteri from the pregnant mice injected with T. gondii ESA at G5, which were transferred intravenously with 2×10⁵ freshly isolated CD4⁺CD25⁺T cells from the mice mentioned above at the first day post injection. The control mice were injected intravenously with 0.2 ml of sterile PBS at the same time. (B) The percentage of CD4⁺CD25⁺ Tregs was reduced at the first day post injection. * p<0.05 the comparison between 0 day and 1 day after post-injection with T. gondii ESA. (C)The abortion rates calculated as the ratio of abortion sites to the total number of implantation sites after the injection of T. gondii ESA. Data represent means ± SD from groups of four mice assayed individually. Statistical differences between groups are shown as follows: *** p<0.001.