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. 2013 Jul 17;8(7):e69830. doi: 10.1371/journal.pone.0069830

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© 2013 Sancheti et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Western blot analyses of the levels of pAkt Ser⁴⁷³ and pGSK3β Ser⁹ in whole brain from nonTg and 3xTg-AD mice +/- lipoic acid. Left panels (A and B) correspond to data from young mice and right panels (C and D) to data from old mice. Bar graphs show the average pAkt Ser⁴⁷³ (normalized to loading control, Akt) and pGSK3β Ser⁹ (normalized to loading control, GSK3β) with error bars indicating ± SEM. Total n = 48, n ≥ 5/group. *P ≤ 0.05, **P ≤ 0.01.