Figure 1. Changes in metabolites within (A) tryptophan, (B) tyrosine and (C) purine metabolism pathways.

Abbreviations: HIOMT  =  hydroxyindole-O-methyltransferase; 5-HIAD  = 5-Hydroxyindole acetyldehyde; NM-5-HT  =  N-methyl serotonin; 5-HTPOL  = 5-Hydroxytryptophol; 5-MIAA  = 5-Methoxyindole acetic acid; 5-MTPM  = 5-methoxytryptamine. For the remaining metabolites, see Table 1.