Table 5. Correlations of pre-treatment levels of ratios of metabolites within the tryptophan pathway to four week percent change in HAMD17 scores in Sertraline group.
| Ratios | Correlation | p-value |
| 5-HTP/TRP | 0.072 | 0.68 |
| 5-HT/TRP | 0.19 | 0.28 |
| NA-5-HT/TRP | −0.28 | 0.10 |
| 5-HIAA/TRP | −0.11 | 0.54 |
| 5-MTPOL/TRP | −0.2 | 0.25 |
| MEL/TRP | −0.26 | 0.14 |
| 5-MTPM/TRP | 0.32 | 0.058 |
| 5-HT/5-HTP | 0.15 | 0.40 |
| NA-5-HT/5-HTP | −0.21 | 0.23 |
| 5-HIAA/5-HTP | −0.17 | 0.34 |
| 5-MTPOL/5-HTP | −0.21 | 0.24 |
| MEL/5-HTP | −0.31 | 0.068 |
| 5-MTPM/5-HTP | 0.22 | 0.19 |
| NA-5-HT/5-HT | −0.33 | 0.051 |
| 5-HIAA/5-HT | −0.33 | 0.054 |
| 5-MTPOL/5-HT | −0.25 | 0.14 |
| MEL/5-HT | −0.38 | 0.024 |
| 5MTPM/5-HT | 0.11 | 0.53 |
| MEL/NA-5-HT | −0.2 | 0.26 |
| MEL/5MTPM | −0.4 | 0.016 |
| NA-5-HT/5MTPM | −0.54 | 0.0007 |
| 5-HIAA/5MTPM | −0.43 | 0.011 |
| 5-MTPOL/5MTPM | −0.28 | 0.11 |
Note: A positive correlation coefficient indicates that responders favor higher ratios.
Abbreviations: 5-MTPM = 5-methoxytryptamine. For the remaining metabolites, see Table 1.