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. Author manuscript; available in PMC: 2013 Jul 17.
Published in final edited form as: Dev Biol. 2007 May 3;307(2):237–247. doi: 10.1016/j.ydbio.2007.04.033

Figure 3. Analysis of epithelial differentiation in Fgf10+/−; Mlc1v-LacZ+/− lungs reveals decreased expression of SP-B and TTF-1.

Figure 3

(A-B) SP-B expression by immuno-histochemistry showing a decrease in SP-B expression in newborn Fgf10+/−; Mlc1v-LacZ+/− lungs (B) compared to control (Fgf10+/−) (A). (C) The number of SP-B labeled cells per section was analyzed. The difference observed between Fgf10+/−; Mlc1v-LacZ+/− (B) and control lung (A) is significant (p < 0,01). (D-E) Immuno-histochemistry with TTF-1 antibody showing a decrease in TTF1 expression in newborn Fgf10+/−; Mlc1v-LacZ+/− lungs (E) compared to control (D). (F) The number of TTF-1 labelled cells per section was analyzed. The difference observed between Fgf10+/−; Mlc1v-LacZ+/− (E) and control lungs (D) is significant (p<0,03). P0- Post natal day 0.