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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Aging Cell. 2013 Jun 5;12(4):645–651. doi: 10.1111/acel.12088

Fig. 3. Parametric analysis of gene-set enrichment (PAGE) of microarray data from humans and rats.

Fig. 3

Fig. 3

Columns show every (A) gene or (B) pathway significantly up-regulated (red) or down-regulated (blue) by CR. (C) The five most highly up-regulated and down-regulated genes, based on Z-ratio in CR compared to WD and AL respectively. (D) Venn diagram showing the pathway interactions between humans and rats (up-regulated and down-regulated pathways are shown in red and blue respectively). (E) Cell plot showing the most highly significant up-regulated (red) and down-regulated (blue) common pathways between humans and rats.