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. Author manuscript; available in PMC: 2014 Aug 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Apr 30;271(1):20–29. doi: 10.1016/j.taap.2013.04.018

Fig. 5. Adding a VEGF neutralizing antibody into the conditioned medium from arsenic-transformed cells reduces tube formation by HUVECs.

Fig. 5

(A, B) Representative images of tube formation by HUVECs (A) and quantification of formed tube branches (means ± standard deviations, n=3) (B) induced by the conditioned medium from As-p53lowHBECs with the addition of a Control antibody or a VEGF neutralizing antibody. Scale bar=200 μm. * p<0.05, compared to Control antibody (Ab) group. Conditioned medium were collected for tube formation assay as described in Materials and Methods. Similar results were obtained in two additional experiments.