Table 2.
Expression of PLCβ isoforms in the cerebellar cortex.
Purkinje cells | UBCs | granule cells | stellate/basket cells | Golgi cells | references | ||
---|---|---|---|---|---|---|---|
Rat | PLCβ1 | ++ 1 | +++ type I | ++ | ++ | - | Vitale et al., 2004 |
PLCβ2 | No data | ||||||
PLCβ3 | ++++/++ /- on-off bands | - | - | - | - | Tanaka and Kondo, 1994 | |
PLCβ4 | ++++ /++ /- on-off bands | ++++ type II | + | - | - | Tanaka and Kondo, 1994; Roustan et al., 1995; Min et al., 2000 | |
Mouse | PLCβ1 | +++/+ 2 | ++ type I | ++ | ++ | - | Watanabe et al., 1998; Hashimoto et al., 2001; Fukaya et al., 2008; Montaña et al., 2012 |
PLCβ2 | - | - | - | - | - | Watanabe et al., 1998; Hashimoto et al., 2001 | |
PLCβ3 | ++++ /++ /- on-off bands | - | - | - | - | Watanabe et al., 1998; Hashimoto et al., 2001; Sarna et al., 2006 | |
PLCβ4 | ++++ /++ /- on-off bands | ++++ type II | ++ | - | - | Watanabe et al., 1998; Hashimoto et al., 2001; Sarna et al., 2006; Chung et al., 2009a, 2009b |
only the peripheral dendrites are immunolabeled.
all Purkinje cells are PLCβ1 immunolabeled, however they show distinct compartmentalization with moderately and lightly stained bands in the molecular layer